{"created":"2023-06-20T16:49:33.530468+00:00","id":6102,"links":{},"metadata":{"_buckets":{"deposit":"ff7b2835-0243-4498-9be1-6671a1c34200"},"_deposit":{"created_by":5,"id":"6102","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"6102"},"status":"published"},"_oai":{"id":"oai:meiji.repo.nii.ac.jp:00006102","sets":["10:1534:1536:1685"]},"author_link":["5562"],"item_5_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2004-12-25","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"8","bibliographicPageStart":"1","bibliographicVolumeNumber":"140","bibliographic_titles":[{"bibliographic_title":"明治大学農学部研究報告"}]}]},"item_5_description_39":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Article","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"真核生物のDNA複製オリジンとして働くDNA配列としては、出芽酵母において唯一、自律複製配列(autonomously replicating sequence: ARS) として確認され、このARS活性に必須な11bpのARSコンセンサス配列(ARS consensus sequence: ACS) が明らかにされた。ORC(origin recognition complex) はACSの塩基配列特異的に結合する6つのサブユニットから構成される複合体として同定され、6つのサブユニットはサイズの大きい順にOrc1～Orc6と命名された。おのおの遺伝子ノックアウトにより、それらが増殖に必須であることが示されている。出芽酵母Orcサブユニットのホモログは他の生物種でも報告されている。分裂酵母のOrc2は、two-hybridによってCdc2と結合するタンパク質として同定された。","subitem_description_type":"Abstract"}]},"item_5_link_63":{"attribute_name":"OPACbibid","attribute_value_mlt":[{"subitem_link_url":"https://opac2018.lib.meiji.ac.jp/webopac/ufirdi.do?ufi_target=ctlsrh&listcnt=5&maxcnt=100&bibid=SB00006030"}]},"item_5_publisher_32":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"明治大学農学部","subitem_publisher_language":"ja"}]},"item_5_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0465-6083","subitem_source_identifier_type":"ISSN"}]},"item_5_source_id_9":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AN00239079","subitem_source_identifier_type":"NCID"}]},"item_5_version_type_15":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"吉田, 健一"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_login","displaytype":"detail","filename":"nogakubuhokoku_140_1.pdf","filesize":[{"value":"398.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"学内限定公開(学外からはログイン要求され閲覧不可)","url":"https://meiji.repo.nii.ac.jp/record/6102/files/nogakubuhokoku_140_1.pdf"},"version_id":"5ca66ba5-2d20-4027-9a0a-61f62c4de6ef"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ヒトDNA複製因子による転写制御","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒトDNA複製因子による転写制御","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"5","path":["1685"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2009-04-18"},"publish_date":"2009-04-18","publish_status":"0","recid":"6102","relation_version_is_last":true,"title":["ヒトDNA複製因子による転写制御"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-09-06T19:54:08.493101+00:00"}